The REC8 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to mrec, REC8, and Rec8p. This antibody recognizes Human antigen. The REC8 Antibody has been validated for the following applications: Western Blot.
Description
Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II By similarity.Parisi S., Mol. Cell. Biol. 19:3515-3528(1999).Ota T., Nat. Genet. 36:40-45(2004).Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases